Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.36 |
| ▸ | CCR3 | P51677 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | HTR7 | P34969 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916920 | 0.94 | CTSS (0.41) | CTSSMCHR1CCR3HTR2AHTR7 | |
| SCHEMBL8916788 | 0.93 | CTSS (0.42) | CTSSMCHR1CCR3HTR2AHTR7 | |
| Oxalic Acid SCHEMBL8991806 | 0.92 | CTSS (0.40) | CTSSMCHR1CCR3HTR2AHTR7 | |
| SCHEMBL8919136 | 0.87 | CTSS (0.40) | CTSSMCHR1CCR3HTR2AHTR7 | |
| SCHEMBL8916713 | 0.86 | SLC6A4 (0.39) | CTSSMCHR1CCR3HTR2AHTR7 | |
| SCHEMBL8917540 | 0.86 | HTR1D (0.49) | CTSSMCHR1HTR2AHTR7KCNH2 | |
| Oxalic Acid SCHEMBL8919091 | 0.84 | CTSS (0.43) | CTSSMCHR1CCR3 | |
| SCHEMBL8917101 | 0.84 | DRD2 (0.54) | HTR2AHTR7KCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL8920342 | 0.82 | CTSS (0.49) | CTSSMCHR1HTR2AHTR7KCNH2 | |
| SCHEMBL8916743 | 0.81 | HTR2A (0.51) | HTR2AHTR7KCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |