Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.49 |
| ▸ | HTR1B | P28222 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 7/20 | 0.37 |
| ▸ | HTR7 | P34969 | 7/20 | 0.37 |
| ▸ | DRD2 | P14416 | 7/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918401 | 0.94 | HTR1D (0.49) | HTR1DHTR1BCTSSHTR2AHTR7 | |
| SCHEMBL8917047 | 0.86 | CTSS (0.42) | HTR1DHTR1BCTSSHTR2AHTR7 | |
| SCHEMBL8917101 | 0.86 | DRD2 (0.54) | HTR2AHTR7DRD2KCNH2SLC6A4 | |
| SCHEMBL8916788 | 0.85 | CTSS (0.42) | HTR1DHTR1BCTSSHTR2AHTR7 | |
| SCHEMBL8916713 | 0.85 | SLC6A4 (0.39) | HTR1BCTSSHTR2AHTR7DRD2 | |
| SCHEMBL8916743 | 0.84 | HTR2A (0.51) | HTR2AHTR7DRD2KCNH2SLC6A4 | |
| Hydrochloric Acid SCHEMBL8920342 | 0.81 | CTSS (0.49) | HTR1DHTR1BCTSSHTR2AHTR7 | |
| SCHEMBL8916920 | 0.80 | CTSS (0.41) | CTSSHTR2AHTR7DRD2KCNH2 | |
| SCHEMBL8918089 | 0.80 | DRD2 (0.54) | HTR2AHTR7DRD2KCNH2SLC6A4 | |
| Hydrochloric Acid SCHEMBL8917305 | 0.79 | ACHE (0.36) | HTR1DHTR1BCTSSHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |