Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916426 | 0.93 | MAPT (0.40) | SLC6A4DRD2MCHR1HTR1ACTSS | |
| SCHEMBL8916930 | 0.90 | SLC6A4 (0.52) | SLC6A4DRD2MCHR1HTR1ATP53 | |
| SCHEMBL8917047 | 0.86 | CTSS (0.42) | DRD2MCHR1CTSSBAZ2BCCR3 | |
| SCHEMBL8916788 | 0.86 | CTSS (0.42) | MCHR1CTSSBAZ2BCCR3HTR1B | |
| Hydrochloric Acid SCHEMBL8917305 | 0.86 | ACHE (0.36) | SLC6A4DRD2MCHR1HTR1ACTSS | |
| SCHEMBL8917540 | 0.85 | HTR1D (0.49) | SLC6A4DRD2MCHR1HTR1ACTSS | |
| SCHEMBL8917705 | 0.83 | DRD2 (0.52) | SLC6A4DRD2MCHR1TP53MAPT | |
| SCHEMBL8916680 | 0.82 | HTR2C (0.52) | CYP3A4CYP2D6HTR2AHTR2CHTR7 | |
| Hydrochloric Acid SCHEMBL8920342 | 0.81 | CTSS (0.49) | SLC6A4DRD2MCHR1CTSSHTR1B | |
| SCHEMBL8917101 | 0.81 | DRD2 (0.54) | SLC6A4DRD2HTR2AHTR7DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |