Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 2/20 | 0.36 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917174 | 0.81 | HRH4 (0.38) | ALDH1A1CSNK1A1HRH4HRH3KDM4E | |
| SCHEMBL8916060 | 0.74 | PRKD1 (0.40) | PRKD1PRKD2ALDH1A1HRH4HRH3 | |
| SCHEMBL5502924 | 0.70 | KDM4E (0.52) | ALDH1A1ACACBACACAKDM4EMEN1 | |
| SCHEMBL28605663 | 0.69 | CRBN (0.38) | HRH4HRH3 | |
| SCHEMBL30384988 | 0.69 | CRBN (0.38) | HRH4HRH3 | |
| SCHEMBL8916942 | 0.68 | CYP2D6 (0.49) | MEN1KMT2A | |
| SCHEMBL28607715 | 0.67 | MAPT (0.40) | ALDH1A1 | |
| SCHEMBL8915723 | 0.67 | ATR (0.36) | PRKD1PRKD2ALDH1A1CSNK1A1ACACB | |
| SCHEMBL8921430 | 0.67 | KIT (0.48) | ALDH1A1MEN1KMT2A | |
| SCHEMBL5502137 | 0.66 | NCF1 (0.49) | ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686610-A | Pyridyl piperazine compound | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-11 | — | — | US | disclosed |