Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917059 | 0.81 | PRKD1 (0.36) | HRH4HRH3ALDH1A1KDM4ECSNK1A1 | |
| SCHEMBL30384988 | 0.81 | CRBN (0.38) | HRH4HRH3CYP2D6TSHRCLK4 | |
| SCHEMBL28605663 | 0.81 | CRBN (0.38) | HRH4HRH3CYP2D6TSHRCLK4 | |
| SCHEMBL14854851 | 0.74 | ALDH1A1 (0.34) | ALDH1A1KDM4EHPGD | |
| SCHEMBL8915788 | 0.74 | HTR2C (0.40) | HRH3 | |
| SCHEMBL5502924 | 0.74 | KDM4E (0.52) | ALDH1A1KDM4ESMN1; SMN2CYP2D6TSHR | |
| SCHEMBL5502137 | 0.70 | NCF1 (0.49) | ALDH1A1KDM4ECYP2D6TSHRCLK4 | |
| SCHEMBL15415762 | 0.69 | ALDH1A1 (0.35) | ALDH1A1KDM4ECSNK1A1CYP2D6TSHR | |
| SCHEMBL27591250 | 0.68 | KDM4E (0.56) | ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL20423547 | 0.68 | CRBN (0.57) | ALDH1A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686610-A | Pyridyl piperazine compound | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-11 | — | — | US | disclosed |