Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917188 | 0.86 | PLAU (0.48) | PLAUHTR6L3MBTL1PGRGAA | |
| SCHEMBL8918137 | 0.80 | SLC40A1 (0.40) | MEN1KMT2APOLBSLC40A1KDM4E | |
| SCHEMBL8916300 | 0.80 | MEN1 (0.39) | MEN1KMT2APLAUPOLBHTR6 | |
| SCHEMBL8917282 | 0.77 | PLAU (0.38) | PLAUSLC40A1 | |
| SCHEMBL8916165 | 0.76 | LMNA (0.40) | MEN1KMT2APLAUL3MBTL1GLA | |
| SCHEMBL8918164 | 0.75 | PPARG (0.41) | MEN1KMT2APLAUPGRSLC40A1 | |
| SCHEMBL8694062 | 0.75 | SLC2A1 (0.32) | PLAU | |
| SCHEMBL8916271 | 0.72 | CA1 (0.43) | MEN1KMT2APOLBHTR6L3MBTL1 | |
| SCHEMBL9229107 | 0.70 | CA2 (0.53) | — | |
| SCHEMBL8689434 | 0.70 | ALDH1A1 (0.49) | MEN1KMT2AKEAP1NFE2L2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |