Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365788 | 0.76 | GAA (0.47) | GAAALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL8916181 | 0.75 | ALDH1A1 (0.40) | ALDH1A1HPGDMAPTKMT2AHSD17B10 | |
| SCHEMBL10017671 | 0.73 | GAA (0.48) | GAAALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL2809243 | 0.72 | MAPT (0.56) | GAAALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL9030558 | 0.68 | KDM4E (0.46) | GAAALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL13480743 | 0.67 | ALDH1A1 (0.50) | GAAALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL9367309 | 0.66 | ALDH1A1 (0.49) | GAAALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL17204739 | 0.65 | LMNA (0.44) | GAAALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL9368306 | 0.64 | ALDH1A1 (0.51) | GAAALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL2722861 | 0.64 | ALDH1A1 (0.47) | GAAALDH1A1HPGDMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684165-A | FOR USE IN NONLINEAR OPTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-04 | — | — | US | disclosed |
| US-5432286-A | Nonlinear optics | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-11 | — | — | US | disclosed |
| EP-0592919-A1 | Substituted thieno[3,2-b]thiophenes and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-20 | — | — | EP | disclosed |