Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.50 |
| ▸ | GAPDH | P04406 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10396062 | 0.98 | MAPT (0.48) | MAPTTRPA1DDAH1GAPDHFFAR1 | |
| SCHEMBL30568786 | 0.93 | ACHE (0.42) | MAPTTRPA1DDAH1GAPDHFFAR1 | |
| SCHEMBL28777499 | 0.79 | SQLE (0.35) | MAPTTRPA1DDAH1GAPDHFFAR1 | |
| SCHEMBL1784022 | 0.79 | TRPA1 (0.48) | MAPTTRPA1DDAH1GAPDHFFAR1 | |
| SCHEMBL1784024 | 0.79 | TRPA1 (0.48) | MAPTTRPA1DDAH1GAPDHFFAR1 | |
| SCHEMBL7740753 | 0.78 | SQLE (0.41) | MAPTFFAR4 | |
| SCHEMBL7740751 | 0.78 | SQLE (0.41) | MAPTFFAR4 | |
| SCHEMBL10743532 | 0.78 | KMT2A (0.45) | MAPTTRPA1DDAH1GAPDHCYP3A4 | |
| SCHEMBL9250466 | 0.78 | SQLE (0.34) | — | |
| SCHEMBL943388 | 0.77 | FFAR1 (0.47) | MAPTTRPA1DDAH1GAPDHFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591435-A | Insecticidal or insect behaviorally active preparations from aromatic plants | THE RESEARCH AND DEVELOPMENT INSTITUTE, INC. (US) | 1997-01-07 | — | — | US | claimed |
| CN-113891870-A | Selective hydrogenation of alkynols to enols in the presence of phosphorus compounds | 帝斯曼知识产权资产管理有限公司 | 2022-01-04 | — | — | CN | disclosed |
| CN-113874340-A | Selective hydrogenation of alkynes to alkenes in the presence of phosphorus compounds and organic sulfur compounds | 帝斯曼知识产权资产管理有限公司 | 2021-12-31 | — | — | CN | disclosed |
| EP-3772975-A1 | NOVEL USE OF SUBSTITUTED CHROMAN-6-OLS | DSM IP Assets B.V. (NL) | 2021-02-17 | — | — | EP | disclosed |
| US-20210030022-A1 | NOVEL USE OF SUBSTITUTED CHROMAN-6-OLS | DSM IP ASSETS B.V. (NL) | 2021-02-04 | — | — | US | disclosed |
| WO-2019185891-A1 | NOVEL USE OF SUBSTITUTED CHROMAN-6-OLS | DSM IP ASSETS B.V. (NL) | 2019-10-03 | — | — | WO | disclosed |
| WO-2019185894-A1 | NOVEL USE OF SUBSTITUTED CHROMAN-6-OLS | DSM IP ASSETS B.V. (NL) | 2019-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210030022-A1 | NOVEL USE OF SUBSTITUTED CHROMAN-6-OLS | KMO, FFAR3, ACOX3 | MAPT 4768/4885TRPA1 3151/4885DDAH1 2368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.