Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 10/20 | 0.39 |
| ▸ | TP53 | P04637 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916930 | 0.93 | SLC6A4 (0.52) | DRD2SLC6A4MAPTTP53ALDH1A1 | |
| SCHEMBL8916426 | 0.90 | MAPT (0.40) | DRD2SLC6A4MAPTTP53MEN1 | |
| SCHEMBL8917035 | 0.85 | ACHE (0.46) | MAPTTP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL8916713 | 0.83 | SLC6A4 (0.39) | DRD2SLC6A4MAPTTP53ALDH1A1 | |
| SCHEMBL8917325 | 0.80 | MAPT (0.40) | DRD2SLC6A4MAPTTP53ALDH1A1 | |
| SCHEMBL8917865 | 0.80 | MAPT (0.38) | DRD2MAPTTP53MEN1KMT2A | |
| SCHEMBL8916920 | 0.80 | CTSS (0.41) | DRD2MAPTTP53MEN1KMT2A | |
| SCHEMBL8919111 | 0.79 | DRD2 (0.51) | DRD2SLC6A4 | |
| SCHEMBL8916709 | 0.79 | CTSS (0.49) | DRD2SLC6A4MAPTTP53MEN1 | |
| SCHEMBL8919136 | 0.79 | CTSS (0.40) | MAPTTP53GAAMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |