SCHEMBL8917531

SCHEMBL8917531

Cc1cccc(Br)c1-n1nn[nH]c1=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
DAO P14920 2/20 0.34
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
HCAR1 Q9BXC0 1/20 0.33
FEN1 P39748 1/20 0.33
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33
PDE7A Q13946 2/20 0.32
MAPK13 O15264 1/20 0.32
MAPK12 P53778 1/20 0.32
MAPK11 Q15759 1/20 0.32
MAPK14 Q16539 1/20 0.32
TSHR P16473 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
PBRM1 Q86U86 1/20 0.31
NOS1 P29475 1/20 0.31
AXL P30530 1/20 0.31
S1PR2 O95136 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31398188 1.00 ALDH1A1 (0.34) ALDH1A1DAONPC1RAB9AHCAR1
SCHEMBL8977225 0.89 ALDH1A1 (0.39) ALDH1A1DAOHCAR1MEN1POLB
SCHEMBL8910664 0.89 FEN1 (0.37) ALDH1A1NPC1RAB9AFEN1NPSR1
SCHEMBL15352460 0.81 MAPK14 (0.40) ALDH1A1DAOHCAR1FEN1MEN1
SCHEMBL8598961 0.81 MAPK11 (0.39) ALDH1A1DAONPC1RAB9AKMT2A
SCHEMBL15351721 0.78 JAK2 (0.36) HCAR1FEN1PDE7A
SCHEMBL18546285 0.78 HCAR1 (0.44) DAORAB9AHCAR1PDE7AAURKA
SCHEMBL8977224 0.74 TDP1 (0.43) ALDH1A1DAOHCAR1MEN1POLB
SCHEMBL8160888 0.73 MGLL (0.43) ALDH1A1NPC1RAB9AHCAR1FEN1
SCHEMBL5906376 0.73 ALDH1A1 (0.44) ALDH1A1RAB9AHCAR1MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5635446-A Herbicidal tetrazolinones combined with other herbicides NIRON BAYER AGROCHEM K.K. (JP) 1997-06-03 US disclosed
US-5541336-A Herbicidal tetrazolinones NIHON BAYER AGROCHEM K.K. (JP) 1996-07-30 US disclosed
EP-0672663-A1 Herbicidal tetrazolinones NIHON BAYER AGROCHEM K.K. (JP) 1995-09-20 EP disclosed