SCHEMBL8977225

SCHEMBL8977225

Cc1cccc(C)c1-n1nn[nH]c1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
TSHR P16473 3/20 0.39
NPSR1 Q6W5P4 1/20 0.39
DAO P14920 2/20 0.39
HCAR1 Q9BXC0 1/20 0.37
MEN1 O00255 1/20 0.37
POLB P06746 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPK13 O15264 2/20 0.35
MAPK12 P53778 2/20 0.35
MAPK11 Q15759 2/20 0.35
MAPK14 Q16539 2/20 0.35
GAA P10253 2/20 0.34
AURKA O14965 1/20 0.34
DPP4 P27487 3/20 0.33
ALOX15 P16050 2/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
ANPEP P15144 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8598961 0.89 MAPK11 (0.39) ALDH1A1TSHRDAOKMT2AMAPK13
SCHEMBL15352460 0.89 MAPK14 (0.40) ALDH1A1DAOHCAR1MEN1POLB
SCHEMBL8917531 0.89 ALDH1A1 (0.34) ALDH1A1TSHRNPSR1DAOHCAR1
SCHEMBL8977207 0.81 ALDH1A1 (0.39) ALDH1A1NPSR1DAOMEN1KMT2A
SCHEMBL8977224 0.81 TDP1 (0.43) ALDH1A1TSHRNPSR1DAOHCAR1
SCHEMBL5906376 0.80 ALDH1A1 (0.44) ALDH1A1TSHRHCAR1MEN1POLB
SCHEMBL8686695 0.80 PDE3B (0.33)
SCHEMBL18546285 0.78 HCAR1 (0.44) DAOHCAR1AURKA
SCHEMBL8603440 0.78 P2RX7 (0.36) ALDH1A1NPSR1DAOHCAR1
SCHEMBL18504519 0.78 DAO (0.34) ALDH1A1TSHRDAOHCAR1AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708097-A1 Herbicidally active tetrazolinones NIHON BAYER AGROCHEM K.K. (JP) 1996-04-24 EP disclosed