Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309863 | 0.84 | GAA (0.60) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL8915716 | 0.78 | ADORA1 (0.59) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL1318935 | 0.77 | IKBKB (0.45) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL14833516 | 0.77 | BRAF (0.58) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL8997272 | 0.77 | MAPT (0.44) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL8309622 | 0.76 | MAPT (0.57) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL18988429 | 0.76 | ADORA1 (0.56) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL8918890 | 0.75 | HTT (0.53) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL16197283 | 0.74 | BTK (0.48) | ALDH1A1MAPTLMNAPOLBIKBKB | |
| SCHEMBL4257428 | 0.74 | IKBKB (0.42) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593997-A | 4-aminopyrazolo(3-,4-D)pyrimidine and 4-aminopyrazolo-(3,4-D)pyridine tyrosine kinase inhibitors | PFIZER INC. (US) | 1997-01-14 | — | — | US | disclosed |