Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 15/20 | 0.43 |
| ▸ | F2 | P00734 | 7/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897708 | 0.85 | F7 (0.49) | F7F2ITGB3ITGA2BF10 | |
| SCHEMBL7345488 | 0.84 | ITGB3 (0.54) | ITGB3ITGA2B | |
| SCHEMBL8899227 | 0.83 | ALDH1A1 (0.46) | ITGB3NOX1 | |
| SCHEMBL9389706 | 0.80 | ITGB3 (0.54) | F7F2ITGB3ITGA2B | |
| SCHEMBL7347076 | 0.79 | ITGB3 (0.51) | ITGB3ITGA2B | |
| SCHEMBL8917809 | 0.78 | F7 (0.69) | F7F2ITGB3ITGA2BF10 | |
| SCHEMBL7346087 | 0.78 | ITGB3 (0.53) | ITGB3ITGA2B | |
| SCHEMBL7352608 | 0.76 | ITGB3 (0.52) | ITGB3ITGA2B | |
| SCHEMBL7344836 | 0.76 | ITGB3 (0.51) | ITGB3ITGA2B | |
| SCHEMBL7352179 | 0.76 | ITGB3 (0.68) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624956-A | Urea derivatives useful as platelet aggregation inhibitors | THE MONSANTO COMPANY (US) | 1997-04-29 | — | — | US | claimed |
| WO-1994017041-A1 | AMIDINOPHENYL SUBSTITUTED UREA, THIOUREA OR GUANIDINO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-04 | — | — | WO | claimed |
| US-5624956-A | Urea derivatives useful as platelet aggregation inhibitors | THE MONSANTO COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| US-5475025-A | Urea derivatives useful as platelet aggregation inhibitors | THE MONSANTO COMPANY (US) | 1995-12-12 | — | — | US | disclosed |