Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRE | P78334 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.31 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.31 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915783 | 0.86 | CDC7 (0.36) | PARP1CDC7DBF4GABRPGABRD | |
| SCHEMBL8917631 | 0.85 | CDC7 (0.35) | CDC7DBF4GABRPGABRDGABRA1 | |
| SCHEMBL8916424 | 0.75 | MEN1 (0.47) | HRH3L3MBTL1ALDH1A1NPY5RSIGMAR1 | |
| SCHEMBL8917048 | 0.69 | MEN1 (0.46) | PARP1CDC7DBF4ALDH1A1 | |
| SCHEMBL27153587 | 0.66 | ALDH1A1 (0.45) | PARP1CDC7DBF4L3MBTL1ALDH1A1 | |
| SCHEMBL23142164 | 0.66 | CDC7 (0.44) | PARP1CDC7DBF4 | |
| SCHEMBL18304962 | 0.66 | CDC7 (0.44) | PARP1CDC7DBF4ALDH1A1 | |
| SCHEMBL8916133 | 0.66 | NOTUM (0.33) | ALDH1A1 | |
| SCHEMBL5418727 | 0.64 | KDM4E (0.58) | ALDH1A1 | |
| SCHEMBL8991820 | 0.63 | RYR2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |