Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR2 | Q92736 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.31 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917631 | 0.78 | CDC7 (0.35) | MAPK14GSK3BCASP3 | |
| SCHEMBL8916133 | 0.70 | NOTUM (0.33) | PRKD1MAPK14GSK3B | |
| SCHEMBL9040253 | 0.68 | RYR2 (0.44) | RYR2PRKD3PRKD1PRKD2 | |
| SCHEMBL8991845 | 0.64 | RYR2 (0.43) | RYR2PRKD3PRKD1PRKD2 | |
| SCHEMBL8917854 | 0.63 | PARP1 (0.35) | — | |
| SCHEMBL9429883 | 0.63 | CA2 (0.61) | RYR2PRKD3PRKD1PRKD2 | |
| SCHEMBL11196961 | 0.58 | GSK3B (0.67) | GSK3BCASP3 | |
| SCHEMBL8918044 | 0.57 | ALDH1A1 (0.33) | — | |
| SCHEMBL10972012 | 0.57 | DAO (0.50) | GSK3BCASP3 | |
| SCHEMBL6609187 | 0.57 | GSK3B (0.68) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0596125-A1 | CONDENSED THIOPHENE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |