Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918036 | 0.86 | CYP2C19 (0.50) | MEN1TSHRCYP2C19RAB9AKMT2A | |
| SCHEMBL8917854 | 0.75 | PARP1 (0.35) | HRH3L3MBTL1ALDH1A1NPY5RSIGMAR1 | |
| SCHEMBL8920666 | 0.71 | DRD2 (0.57) | MEN1TSHRCYP2C19KMT2ASIGMAR1 | |
| SCHEMBL8916897 | 0.68 | HTR1A (0.59) | KMT2AALDH1A1MAPT | |
| SCHEMBL8915779 | 0.68 | RAB9A (0.93) | MEN1TSHRCYP2C19RAB9AKMT2A | |
| SCHEMBL26983413 | 0.65 | KDM4E (0.46) | MEN1TSHRCYP2C19RAB9AKMT2A | |
| SCHEMBL19228585 | 0.65 | RAB9A (0.60) | MEN1TSHRCYP2C19RAB9AKMT2A | |
| SCHEMBL8917940 | 0.62 | MEN1 (0.53) | MEN1TSHRCYP2C19RAB9AKMT2A | |
| SCHEMBL31411868 | 0.61 | HPGD (0.47) | MEN1TSHRCYP2C19RAB9AKMT2A | |
| SCHEMBL8915783 | 0.60 | CDC7 (0.36) | MEN1CYP2C19KMT2ADAOTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0596125-A1 | CONDENSED THIOPHENE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |