Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CCKBR | P32239 | 2/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912018 | 0.94 | ALDH1A1 (0.39) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL8911896 | 0.87 | ATM (0.38) | ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL8913772 | 0.87 | ITGB3 (0.39) | ALDH1A1NPSR1RAB9A | |
| SCHEMBL8917896 | 0.87 | ATM (0.47) | MEN1KMT2AALDH1A1HPGDPPIA | |
| SCHEMBL8912045 | 0.86 | ALDH1A1 (0.43) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL8911361 | 0.85 | NPSR1 (0.39) | ALDH1A1HPGDSMN1; SMN2NPSR1TP53 | |
| SCHEMBL8911768 | 0.82 | ALDH1A1 (0.39) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL8913843 | 0.81 | NPSR1 (0.36) | ALDH1A1SMN1; SMN2NPSR1RAB9A | |
| SCHEMBL8912021 | 0.80 | ATM (0.51) | NPSR1 | |
| SCHEMBL8913653 | 0.80 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799230-A1 | THIENOXAZINONE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996019482-A1 | THIENOXAZINONE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1996-06-27 | — | — | WO | disclosed |