SCHEMBL891791

SCHEMBL891791

C/C=C/c1ccc(C(=O)O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
FBP1 P09467 1/20 0.55
TP53 P04637 3/20 0.55
TSHR P16473 2/20 0.55
TDP1 Q9NUW8 2/20 0.53
GLA P06280 1/20 0.53
POLB P06746 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
KMT2A Q03164 1/20 0.52
XDH P47989 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
CYP3A4 P08684 2/20 0.49
MAPT P10636 1/20 0.49
ALOX15 P16050 1/20 0.49
MAPK1 P28482 1/20 0.49
BLM P54132 1/20 0.49
CASP7 P55210 1/20 0.49
HSD17B10 Q99714 1/20 0.49
RARA P10276 1/20 0.49
RARB P10826 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL199971 1.00 ALDH1A1 (0.58) ALDH1A1FBP1TP53TSHRTDP1
SCHEMBL7564116 1.00 ALDH1A1 (0.58) ALDH1A1FBP1TP53TSHRTDP1
Oxirane SCHEMBL29253108 0.90 ALDH1A1 (0.48) ALDH1A1FBP1TP53TSHRTDP1
SCHEMBL12791487 0.89 TRPA1 (0.58) ALDH1A1FBP1TP53TSHRTDP1
Anethole SCHEMBL30697265 0.87 XDH (0.71) ALDH1A1TP53TSHRTDP1KMT2A
SCHEMBL9681086 0.85 ALDH1A1 (0.68) ALDH1A1FBP1TP53TSHRTDP1
SCHEMBL9339856 0.85 ALDH1A1 (0.68) ALDH1A1FBP1TP53TSHRTDP1
SCHEMBL69167 0.85 ALDH1A1 (0.68) ALDH1A1FBP1TP53TSHRTDP1
SCHEMBL2615887 0.85 ALDH1A1 (0.68) ALDH1A1FBP1TP53TSHRTDP1
SCHEMBL9681088 0.85 ALDH1A1 (0.68) ALDH1A1FBP1TP53TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102887992-A Polyester/polyethylene glycol block copolymer containing side cinnamoyl group and application thereof UNIV TIANJIN 2013-01-23 CN claimed
EP-0079639-B1 A NEW ANTI-INFLAMMATORY DRUG SPA SOCIETA' PRODOTTI ANTIBIOTICI S.p.A. (IT) 1985-07-24 EP claimed
WO-2023215514-A2 BIOLUMINESCENCE-TRIGGERED PHOTOCATALYTIC LABELING PROMEGA CORPORATION (US) 2023-11-09 WO disclosed
US-10329575-B2 Regulatory sequence for plants CERES, INC. (US) 2019-06-25 US disclosed
US-20180223303-A1 SEQUENCE-DETERMINED DNA FRAGMENTS AND CORRESPONDING POLYPEPTIDES ENCODED THEREBY CERES INC (US) 2018-08-09 US disclosed
WO-2017173975-A1 METHOD FOR SYNTHESIZING COMPOUND CONTAINING NON-TERMINAL DOUBLE BOND 中国科学院福建物质结构研究所 2017-10-12 WO disclosed
EP-2875023-B1 OCTAHYDRO-CYCLOPENTAPYRROLYL ANTAGONISTS OF CCR2 JANSSEN PHARMACEUTICA NV (BE) 2017-04-05 EP disclosed
US-20170037426-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby ALEXANDROV NICKOLAI (US) 2017-02-09 US disclosed
US-20160076046-A1 PROMOTER, PROMOTER CONTROL ELEMENTS, AND COMBINATIONS, AND USES THEREOF CERES, INC. (US) 2016-03-17 US disclosed
US-9029523-B2 Promoter, promoter control elements, and combinations, and uses thereof CERES, INC. (US) 2015-05-12 US disclosed
US-9024017-B2 Octahydro-cyclopentapyrrolyl antagonists of CCR2 JANSSEN PHARMACEUTICA NV (BE) 2015-05-05 US disclosed
US-20120159672-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby CERES, INC. 2012-06-21 US disclosed
US-20120084885-A1 Promoter, promoter control elements, and combinations, and uses thereof ALEXANDROV NICKOLAI (US) 2012-04-05 US disclosed
US-20110191912-A1 Promoter, promoter control elements, and combinations, and uses thereof ALEXANDROV NICKOLAI 2011-08-04 US disclosed
US-20100037355-A1 SEQUENCE-DETERMINED DNA FRAGMENTS AND CORRESPONDING POLYPEPTIDES ENCODED THEREBY CERES, INC (US) 2010-02-11 US disclosed
US-20090265815-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded therapy ALEXANDROV NICKOLAI 2009-10-22 US disclosed
US-20070214517-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby CERES, INC. (US) 2007-09-13 US disclosed
US-20060150283-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby ALEXANDROV NICKOLAI 2006-07-06 US disclosed
US-20060048240-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby ALEXANDROV NICKOLAI 2006-03-02 US disclosed
EP-0079639-B1 A NEW ANTI-INFLAMMATORY DRUG SPA SOCIETA' PRODOTTI ANTIBIOTICI S.p.A. (IT) 1985-07-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170037426-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby RNGTT, CPSF1, CPSF6 ALDH1A1 4769/4885FBP1 1716/4885TP53 676/4885
US-20120084885-A1 Promoter, promoter control elements, and combinations, and uses thereof RNGTT, GTF3C5, GTF3C1 ALDH1A1 4633/4885FBP1 1026/4885TP53 846/4885
US-20070214517-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby RNGTT, CPSF1, CPSF6 ALDH1A1 4769/4885FBP1 1716/4885TP53 676/4885
US-20110191912-A1 Promoter, promoter control elements, and combinations, and uses thereof RNGTT, GTF3C5, GTF3C1 ALDH1A1 4635/4885FBP1 1081/4885TP53 871/4885
US-20120159672-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby RNGTT, CPSF1, CPSF6 ALDH1A1 4769/4885FBP1 1716/4885TP53 676/4885
US-20100037355-A1 SEQUENCE-DETERMINED DNA FRAGMENTS AND CORRESPONDING POLYPEPTIDES ENCODED THEREBY RNGTT, CPSF1, CPSF6 ALDH1A1 4769/4885FBP1 1716/4885TP53 676/4885
US-20060048240-A1 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby RNGTT, CPSF1, CPSF6 ALDH1A1 4769/4885FBP1 1716/4885TP53 676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.