SCHEMBL8918103

SCHEMBL8918103

COCCOC(=O)COC=O

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
DGKA P23743 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MET P08581 1/20 0.31
ADORA2A P29274 1/20 0.30
ADRA2A P08913 1/20 0.30
ADRA1A P35348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8918469 0.94 TSHR (0.35) TSHR
SCHEMBL8918614 0.85 TSHR (0.31) TSHR
SCHEMBL3364080 0.81 HCAR2 (0.41) TSHRDGKASMN1; SMN2
SCHEMBL8920157 0.80 ALDH1A1 (0.50) TSHRDGKASMN1; SMN2
SCHEMBL9936704 0.80 TSHR (0.43) TSHRDGKASMN1; SMN2ADRA2AADRA1A
SCHEMBL8919238 0.79
SCHEMBL8919017 0.79 ALDH1A1 (0.48) TSHRDGKASMN1; SMN2
SCHEMBL12050130 0.78 TSHR (0.42) TSHRDGKASMN1; SMN2ADRA2AADRA1A
SCHEMBL3364135 0.78 ATM (0.50) TSHRDGKA
SCHEMBL8919700 0.77 DGKA (0.36) TSHRDGKAADRA2AADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8834749-B2 Photosensitive resin composition and light blocking layer using the same CHEIL INDUSTRIES INC. (KR) 2014-09-16 US disclosed
US-8835492-B2 Temperature and pH sensitive block copolymer and polymeric hydrogels using the same SUNGYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2014-09-16 US disclosed
US-20140175343-A1 Photosensitive Resin Composition and Light Blocking Layer Using the Same CHEIL INDUSTRIES INC. (KR) 2014-06-26 US disclosed
US-20080293827-A1 Temperature and Ph Sensitive Block Copolymer and Polymeric Hydrogels Using the Same SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR COROPORATE COLLABORATION (KR) 2008-11-27 US disclosed
US-5620944-A PRE- AND POST-EMERGENT WEED CONTROL NIHON NOHYAKU CO., LTD. (JP) 1997-04-15 US disclosed
EP-0590834-B1 Phenylimidazole derivatives, processes for production thereof, herbicides comprising said derivatives, and usages of said herbicides NIHON NOHYAKU CO LTD (JP) 1996-12-11 EP disclosed
EP-0590834-A1 Phenylimidazole derivatives, processes for production thereof, herbicides comprising said derivatives, and usages of said herbicides NIHON NOHYAKU CO., LTD. (JP) 1994-04-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293827-A1 Temperature and Ph Sensitive Block Copolymer and Polymeric Hydrogels Using the Same LRBA, DAO, PAM TSHR 1591/4885DGKA 639/4885SMN1; SMN2 4026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.