Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.42 |
| ▸ | TMPRSS4 | Q9NRS4 | 3/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20855926 | 0.89 | CA1 (0.58) | CA1CA2P2RX1KCNMA1ALDH1A1 | |
| SCHEMBL9823872 | 0.84 | ALDH1A1 (0.53) | CA1CA2P2RX1KCNMA1ALDH1A1 | |
| SCHEMBL8917003 | 0.81 | CSNK2A1 (0.50) | P2RX1ALDH1A1HPGDGAATMPRSS4 | |
| SCHEMBL4496800 | 0.77 | MGLL (0.51) | CA1CA2MGLL | |
| SCHEMBL2297101 | 0.75 | MGLL (0.58) | MAPTKMT2AMEN1LMNATP53 | |
| SCHEMBL4670848 | 0.73 | CES2 (0.48) | ALDH1A1HPGDGAAMAPTKMT2A | |
| SCHEMBL4676459 | 0.73 | NPSR1 (0.58) | ALDH1A1KMT2AMEN1NPC1LMNA | |
| SCHEMBL4115726 | 0.71 | CA12 (0.55) | CA1CA2ALDH1A1GAANPSR1 | |
| SCHEMBL13538224 | 0.70 | ALDH1A1 (0.42) | CA1CA2ALDH1A1KMT2AKDM4E | |
| SCHEMBL2471282 | 0.70 | RECQL (0.56) | ALDH1A1KMT2AKDM4ETDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |