Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069168 | 0.89 | CSNK2A1 (0.58) | CSNK2A1KMT2AKDM4ELMNAMEN1 | |
| SCHEMBL8918173 | 0.81 | CA1 (0.50) | KMT2AKDM4ELMNAMEN1RAB9A | |
| SCHEMBL4670951 | 0.75 | KMT2A (0.62) | KMT2ALMNAMEN1RAB9AALDH1A1 | |
| SCHEMBL4671330 | 0.73 | ALDH1A1 (0.55) | KMT2AKDM4EMEN1RAB9AALDH1A1 | |
| SCHEMBL4671427 | 0.72 | HSD11B1 (0.45) | KMT2AMEN1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL4115726 | 0.71 | CA12 (0.55) | GAAALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL19795014 | 0.70 | MEN1 (0.44) | CSNK2A1KMT2ALMNAMEN1RAB9A | |
| SCHEMBL1341532 | 0.70 | MAPT (0.49) | CSNK2A1KMT2AMEN1RAB9AGAA | |
| SCHEMBL11500852 | 0.69 | CSNK2A1 (0.72) | CSNK2A1KMT2AKDM4ELMNAMEN1 | |
| SCHEMBL12442147 | 0.69 | KMT2A (0.50) | KMT2AKDM4EMEN1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |