Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 3/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919042 | 1.00 | PDE5A (0.37) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8919955 | 0.86 | ALDH1A1 (0.36) | MEN1MAPTHTR2BSLC6A3KMT2A | |
| SCHEMBL8918266 | 0.84 | PDE5A (0.36) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8919048 | 0.84 | PDE5A (0.36) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8919749 | 0.82 | PRKCA (0.43) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8919132 | 0.82 | PRKCA (0.43) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9090381 | 0.79 | PDE5A (0.34) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8922193 | 0.79 | CYP1A2 (0.38) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8920592 | 0.79 | NPC1 (0.34) | PDE4B | |
| SCHEMBL7827943 | 0.79 | PDE5A (0.39) | PDE5APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691272-A | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0679640-A1 | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-11-02 | — | — | EP | disclosed |