SCHEMBL8920592

SCHEMBL8920592

COc1cccc2c1C1(NC2=N)OCCO1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.34
PIK3CG P48736 1/20 0.34
HTR5A P47898 1/20 0.33
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
CA7 P43166 2/20 0.33
CA9 Q16790 2/20 0.33
ACHE P22303 1/20 0.33
PIM1 P11309 1/20 0.32
RET P07949 1/20 0.32
TXNRD1 Q16881 1/20 0.32
TXNRD3 Q86VQ6 1/20 0.32
TXNRD2 Q9NNW7 1/20 0.32
CA4 P22748 2/20 0.32
CA6 P23280 1/20 0.32
HTR7 P34969 1/20 0.32
TOP1 P11387 1/20 0.32
STK10 O94804 1/20 0.32
SLK Q9H2G2 1/20 0.32
GSK3B P49841 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8919955 0.84 ALDH1A1 (0.36) GSK3A
SCHEMBL8917800 0.81 SLC6A2 (0.35) STK10SLK
SCHEMBL8921478 0.78 TXNRD1 (0.42) CA1CA2CA7CA9TXNRD1
SCHEMBL8919799 0.76 NSD2 (0.35) PIK3CGGSK3BGSK3A
SCHEMBL7831463 0.74 CA1 (0.36) NPC1HTR5ACA1CA2CA7
SCHEMBL8920911 0.72 DDB1 (0.33)
SCHEMBL8922881 0.72 ORAI1 (0.30) ACHE
SCHEMBL8920932 0.69 PDE7A (0.38) HTR5ACA1CA2CA7CA9
SCHEMBL8919166 0.66 PDK2 (0.39)
SCHEMBL8917808 0.65 SLC6A2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
CN-1114431-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS (JP) 1996-01-03 CN disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed