SCHEMBL89185

SCHEMBL89185

O=C(O)/C=C/c1cccc(O)c1O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 2/20 0.71
CA1 P00915 1/20 0.71
CA2 P00918 1/20 0.71
CA4 P22748 1/20 0.71
IAPP P10997 4/20 0.70
BACE1 P56817 1/20 0.57
ERN1 O75460 1/20 0.55
ALOX5 P09917 1/20 0.55
JUN P05412 1/20 0.52
NFE2L2 Q16236 1/20 0.52
PTGER1 P34995 1/20 0.50
PTGER4 P35408 1/20 0.50
PTGER3 P43115 1/20 0.50
PTGER2 P43116 1/20 0.50
KDM4E B2RXH2 1/20 0.49
MAPT P10636 2/20 0.48
LMNA P02545 1/20 0.48
POLB P06746 1/20 0.48
GAA P10253 1/20 0.48
RAB9A P51151 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31083592 1.00 NFKB1 (0.71) NFKB1CA1CA2CA4IAPP
SCHEMBL31256670 1.00 NFKB1 (0.71) NFKB1CA1CA2CA4IAPP
SCHEMBL307296 1.00 NFKB1 (0.71) NFKB1CA1CA2CA4IAPP
SCHEMBL12189733 0.85 IAPP (0.66) NFKB1CA1CA2CA4IAPP
SCHEMBL9094389 0.84 NFKB1 (0.66) NFKB1CA1CA2CA4IAPP
O-Coumaric Acid SCHEMBL29368085 0.83 NFKB1 (1.00) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL892006 0.83 NFKB1 (1.00) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL29367602 0.83 NFKB1 (1.00) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL64885 0.83 NFKB1 (1.00) NFKB1CA1CA2CA4JUN
O-Coumaric Acid SCHEMBL29353381 0.83 NFKB1 (1.00) NFKB1CA1CA2CA4JUN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2676 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250092179-A1 PHOTOSTABLE COMPOSITIONS COMPRISING PARA-ALKOXYL PHENYL SUBSTITUTED PROPENOIC ACID (APP) COPOLYMER DERIVATIVES HallStar Beauty and Personal Care Innovations Company 2025-03-20 US claimed
US-12162972-B2 Photostable compositions comprising para-alkoxyl phenyl substituted propenoic acid (APP) copolymer derivatives HallStar Beauty and Personal Care Innovations Company (US) 2024-12-10 US claimed
CN-118615211-A Mask composition and preparation method thereof 上海金沣铭生物科技有限公司 2024-09-10 CN claimed
US-12076316-B2 Levorphanol prodrugs and processes for making and using them ZEVRA THERAPEUTICS INC. 2024-09-03 US claimed
US-20240026056-A1 PHOTOSTABLE COMPOSITIONS COMPRISING PARA-ALKOXYL PHENYL SUBSTITUTED PROPENOIC ACID (APP) COPOLYMER DERIVATIVES BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2024-01-25 US claimed
CN-117295483-A Cosmetic product for dyeing keratin fibres 花王株式会社 2023-12-26 CN claimed
CN-114539948-B Aqueous binder and application thereof 远景动力技术(江苏)有限公司 2023-12-05 CN claimed
US-11767392-B2 Photostable compositions comprising para-alkoxyl phenyl substituted propenoic acid (APP) copolymer derivatives HallStar Beauty and Personal Care Innovations Company (US) 2023-09-26 US claimed
CN-114870102-B Double-sided vascular stent with nitric oxide catalytic release function and preparation method thereof 东莞市人民医院 2023-08-25 CN claimed
EP-3423429-B1 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY UNIV DE MONCTON (CA) 2023-07-12 EP claimed
US-5552135-A OAT EXTRACT WITH VEHICLES FOR RADITION RESISTANCE ESTEE LAUDER, INC. (US) 1996-09-03 US claimed
EP-0686023-A4 SUNSCREENS CONTAINING PLANT EXTRACTS ESTEE LAUDER INC (US) 1996-02-07 EP claimed
EP-0686023-A1 SUNSCREENS CONTAINING PLANT EXTRACTS ESTEE LAUDER INC. (US) 1995-12-13 EP claimed
WO-1995022576-A1 ADHESION SYSTEM BEAVER MANUFACTURING COMPANY, INC. (US) 1995-08-24 WO claimed
WO-1994018933-A1 SUNSCREENS CONTAINING PLANT EXTRACTS ESTEE LAUDER, INC. (US) 1994-09-01 WO claimed
US-4302199-A Hair dyeing method THE PROCTER & GAMBLE COMPANY (US) 1981-11-24 US claimed
EP-0036534-A1 An orally administrable drug form comprising a beta-lactam antibiotic and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-30 EP claimed
EP-0036145-A1 An orally administered drug form comprising a polar bioactive agent and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-23 EP claimed
EP-0035770-A2 An orally administered drug form comprising a glycosidic antibiotic and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-16 EP claimed
EP-0031561-A2 A rectally administered suppository comprising a drug and an adjuvant MERCK & CO. INC. (US) 1981-07-08 EP claimed