Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.66 |
| ▸ | CA4 | P22748 | 1/20 | 0.66 |
| ▸ | IAPP | P10997 | 4/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.50 |
| ▸ | JUN | P05412 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641080 | 0.88 | NFKB1 (0.72) | NFKB1CA1CA2CA4IAPP | |
| SCHEMBL9297750 | 0.86 | NFKB1 (0.67) | NFKB1CA1CA2CA4PTGER1 | |
| SCHEMBL31083592 | 0.84 | NFKB1 (0.71) | NFKB1CA1CA2CA4IAPP | |
| SCHEMBL307296 | 0.84 | NFKB1 (0.71) | NFKB1CA1CA2CA4IAPP | |
| SCHEMBL89185 | 0.84 | NFKB1 (0.71) | NFKB1CA1CA2CA4IAPP | |
| SCHEMBL31256670 | 0.84 | NFKB1 (0.71) | NFKB1CA1CA2CA4IAPP | |
| SCHEMBL4593147 | 0.84 | PTGER3 (0.58) | NFKB1CA1CA2CA4PTGER1 | |
| SCHEMBL30117591 | 0.84 | NFKB1 (0.53) | NFKB1CA1CA2CA4IAPP | |
| O-Coumaric Acid SCHEMBL64885 | 0.80 | NFKB1 (1.00) | NFKB1CA1CA2CA4JUN | |
| O-Coumaric Acid SCHEMBL892006 | 0.80 | NFKB1 (1.00) | NFKB1CA1CA2CA4JUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500443-A | SCHIZOPHRENIA | ADIR ET COMPAGNIE (FR) | 1996-03-19 | — | — | US | disclosed |