SCHEMBL891852

SCHEMBL891852

CC(O)c1ccc(C(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.57
TP53 P04637 1/20 0.57
ALDH1A1 P00352 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
KMT2A Q03164 1/20 0.52
SRD5A2 P31213 3/20 0.50
ANPEP P15144 1/20 0.48
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
CA12 O43570 1/20 0.48
CA3 P07451 1/20 0.48
TYR P14679 1/20 0.48
DRD1 P21728 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
CA5B Q9Y2D0 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6911963 1.00 TSHR (0.57) TSHRTP53ALDH1A1SMN1; SMN2KMT2A
SCHEMBL6912492 1.00 TSHR (0.57) TSHRTP53ALDH1A1SMN1; SMN2KMT2A
SCHEMBL9330598 0.94 RXRA (0.56) TSHRTP53ALDH1A1SMN1; SMN2KMT2A
Terephthalic Acid SCHEMBL4243136 0.85 TSHR (0.71) TSHRTP53ALDH1A1SMN1; SMN2KMT2A
Terephthalic Acid SCHEMBL338413 0.85 TSHR (0.71) TSHRTP53ALDH1A1SMN1; SMN2KMT2A
Terephthalic Acid SCHEMBL28509987 0.85 TSHR (0.71) TSHRTP53ALDH1A1SMN1; SMN2KMT2A
SCHEMBL18039464 0.84 RXRA (0.47) SRD5A2CA1CA2CA12CA9
SCHEMBL372015 0.83 TSHR (0.60) TSHRTP53ALDH1A1SMN1; SMN2KMT2A
SCHEMBL31192242 0.83 TSHR (0.60) TSHRTP53ALDH1A1SMN1; SMN2KMT2A
SCHEMBL28847652 0.83 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2SRD5A2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823976-A Chemical-enzyme integrated catalyst for oxygen functionalization reaction of inert C-H bond, preparation and application thereof 河北工业大学 2025-04-15 CN claimed
US-20240150300-A1 S-CONFIGURATION-CONTAINING AMINO BENZAMIDE PYRIDAZINONE COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2024-05-09 US claimed
CN-117943084-A Transition metal catalyst, preparation method and method for preparing organic acid by oxidation and pyrolysis of secondary alcohol 中国科学院大连化学物理研究所 2024-04-30 CN claimed
EP-4296266-A1 S-CONFIGURATION-CONTAINING AMINO BENZAMIDE PYRIDAZINONE COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) 2023-12-27 EP claimed
CN-114957132-A S-configuration-containing aminobenzamide pyridazinone compound, preparation method thereof, pharmaceutical composition and application 中国科学院上海药物研究所 2022-08-30 CN claimed
US-10906933-B2 Coupled peptide chain for dissolving poorly soluble polypeptides and application thereof for separation and purification in liquid chromatography SPEC-CHEM INDUSTRY INC. (CN) 2021-02-02 US claimed
EP-2406257-B1 A NEW METHOD FOR THE PREPARATION OF SOLIFENACIN AND NEW INTERMEDIATE THEREOF MEGAFINE PHARMA P LTD (IN) 2019-08-07 EP claimed
CN-109134410-A The synthetic method of fluoro- 3- methyl isobenzofuran -1 (3H) -one of 5- 沈阳药科大学 2019-01-04 CN claimed
US-20180186830-A1 COUPLED PEPTIDE CHAIN FOR DISSOLVING POORLY SOLUBLE POLYPEPTIDES AND APPLICATION THEREOF FOR SEPARATION AND PURIFICATION IN LIQUID CHROMATOGRAPHY SPEC-CHEM INDUSTRY INC. (CN) 2018-07-05 US claimed
CN-105001298-B A kind of synthesis isolation and purification method of indissoluble polypeptide 南京斯拜科生化实业有限公司 2018-01-02 CN claimed
CN-105001307-B A kind of coupling peptide chain dissolving indissoluble polypeptide and application isolated and purified in liquid chromatograph thereof 南京斯拜科生化实业有限公司 2016-08-24 CN claimed
CN-105001298-A Synthesis-separation and purification method for indissolvable polypeptide SPEC CHEM INDUSTRY INC 2015-10-28 CN claimed
CN-105001307-A Coupling peptide chain capable of dissolving indissolvable polypeptide and application of the same in separation and purification in liquid chromatogram SPEC CHEM INDUSTRY INC 2015-10-28 CN claimed
EP-1283286-B1 Microfiber substrate and its manufacturing SAN FANG CHEMICAL INDUSTRY CO (TW) 2005-09-28 EP claimed
EP-0443742-B1 Presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 1997-10-01 EP claimed
US-5476754-A Presensitized; hydrophilic surface on substrate; light sensitive layer containing alkaline water-soluble photocrosslinkable copolycondensed diazo resin FUJI PHOTO FILM CO., LTD. (JP) 1995-12-19 US claimed
EP-0443742-A2 Presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1991-08-28 EP claimed
US-4645662-A PREVENTING AND REMEDYING DENTAL HYPERSENSITIVITY LION CORPORATION (JP) 1987-02-24 US claimed
JP-1224349-A None JP disclosed
US-3945959-A ELECTRICAL INSULATION, CONDUCTORS THE P. D. GEORGE CO. (US) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240150300-A1 S-CONFIGURATION-CONTAINING AMINO BENZAMIDE PYRIDAZINONE COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF HDAC11, HDAC1, HDAC10 TSHR 4094/4885TP53 788/4885ALDH1A1 764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.