Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.34 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919987 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2HTTRAB9A | |
| SCHEMBL8919846 | 0.81 | KDM4E (0.51) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL17844425 | 0.76 | P2RX7 (0.66) | P2RX7FAAHGRM4MMP13SMN1; SMN2 | |
| SCHEMBL8918226 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL8921545 | 0.74 | THRB (0.54) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8921547 | 0.74 | THRB (0.54) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8920234 | 0.74 | THRB (0.54) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8918493 | 0.74 | SIRT3 (0.40) | SMN1; SMN2SIRT3 | |
| SCHEMBL8918123 | 0.73 | LMNA (0.37) | P2RX7SMN1; SMN2NPC1 | |
| SCHEMBL8918190 | 0.73 | P2RX7 (0.52) | P2RX7SMN1; SMN2HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691366-A | UNSATURATED NITRO OXIME FORMED BY REACTION OF DINITROGEN TRIOXIDE WITH DIOLEFIN ETHER, SULFIDE OR AMINE TO BE USED AS VASODILATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |