Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.40 |
| ▸ | DPP4 | P27487 | 7/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | BCL9 | O00512 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | IL2RA | P01589 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | IL2 | P60568 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578262 | 0.92 | CHRNB2 (0.39) | CHRNB2CHRNA4CHRNB4CHRNA3BCHE | |
| SCHEMBL8578269 | 0.92 | CHRNB2 (0.39) | CHRNB2CHRNA4CHRNB4CHRNA3BCHE | |
| Trifluoroacetic Acid SCHEMBL8578978 | 0.87 | CHRNB2 (0.41) | DPP8DPP7CHRNB2CHRNA4CHRNB4 | |
| Trifluoroacetic Acid SCHEMBL8917318 | 0.82 | CHRNB2 (0.41) | DPP8DPP7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL3655590 | 0.76 | POLB (0.44) | CHRNB2CHRNA4CHRNB4CHRNA3GRM3 | |
| SCHEMBL3778464 | 0.76 | POLB (0.44) | CHRNB2CHRNA4CHRNB4CHRNA3GRM3 | |
| SCHEMBL22370868 | 0.75 | CHRNB2 (0.40) | CHRNB2CHRNA4CHRNB4CHRNA3BCHE | |
| SCHEMBL8578265 | 0.74 | RAB9A (0.40) | CHRNB2CHRNA4CHRNB4CHRNA3BCHE | |
| SCHEMBL18185628 | 0.74 | NPC1 (0.38) | CHRNB2CHRNA4CHRNB4CHRNA3BCL9 | |
| SCHEMBL8719595 | 0.73 | LMNA (0.45) | CHRNB2CHRNA4CHRNB4CHRNA3BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5595999-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1997-01-21 | — | — | US | disclosed |
| US-5583133-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-12-10 | — | — | US | disclosed |
| US-5393760-A | Cardiovascular disorders, antitumor agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |