Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 15/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 14/20 | 0.37 |
| ▸ | DRD3 | P35462 | 13/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916845 | 0.94 | DRD2 (0.39) | DRD2SLC6A4HTR2ADRD3ALDH1A1 | |
| SCHEMBL8916475 | 0.91 | DRD2 (0.40) | DRD2SLC6A4HTR2ADRD3HTR1A | |
| SCHEMBL8917179 | 0.78 | DRD2 (0.40) | DRD2SLC6A4HTR2ADRD3HTR1A | |
| SCHEMBL8916470 | 0.77 | DRD2 (0.37) | DRD2SLC6A4HTR2ADRD3HTR1A | |
| SCHEMBL8918733 | 0.75 | DRD2 (0.38) | DRD2SLC6A4HTR2ADRD3HTR1A | |
| SCHEMBL8919173 | 0.75 | ACHE (0.58) | DRD2SLC6A4HTR2ADRD3HTR1A | |
| SCHEMBL8916891 | 0.72 | DRD2 (0.38) | DRD2SLC6A4HTR2ADRD3HTR1A | |
| Hydrochloric Acid SCHEMBL8916112 | 0.72 | DRD2 (0.37) | DRD2SLC6A4HTR2ADRD3HTR1A | |
| SCHEMBL8916973 | 0.71 | DRD2 (0.40) | DRD2SLC6A4HTR2ADRD3ALDH1A1 | |
| SCHEMBL8915782 | 0.68 | DRD2 (0.38) | DRD2SLC6A4HTR2ADRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |