Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919058 | 1.00 | GAA (0.47) | GAATSHRALOX15HSD17B10USP2 | |
| SCHEMBL353126 | 0.75 | GAA (0.60) | GAATSHRALOX15HSD17B10USP2 | |
| SCHEMBL6360331 | 0.72 | TSHR (0.59) | GAATSHRALOX15HSD17B10USP2 | |
| SCHEMBL8918464 | 0.71 | RAB9A (0.44) | GAATP53SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL8918458 | 0.71 | RAB9A (0.44) | GAATP53SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL14044533 | 0.69 | GAA (0.61) | GAATSHRALOX15HSD17B10USP2 | |
| SCHEMBL8918190 | 0.69 | P2RX7 (0.52) | GAATSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8919987 | 0.69 | SMN1; SMN2 (0.55) | GAATSHRTP53SMN1; SMN2KMT2A | |
| SCHEMBL8920205 | 0.68 | MTNR1A (0.33) | TSHRKDM4E | |
| SCHEMBL8920203 | 0.68 | MTNR1A (0.33) | TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691366-A | UNSATURATED NITRO OXIME FORMED BY REACTION OF DINITROGEN TRIOXIDE WITH DIOLEFIN ETHER, SULFIDE OR AMINE TO BE USED AS VASODILATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |