Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918458 | 1.00 | RAB9A (0.44) | RAB9ARECQLNPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL13754002 | 0.75 | NPC1 (0.59) | RAB9ARECQLNPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8919058 | 0.71 | GAA (0.47) | SMN1; SMN2L3MBTL1TP53GAAALDH1A1 | |
| SCHEMBL8919079 | 0.71 | GAA (0.47) | SMN1; SMN2L3MBTL1TP53GAAALDH1A1 | |
| SCHEMBL19113898 | 0.70 | RAB9A (0.51) | RAB9ARECQLNPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9328693 | 0.69 | RAB9A (0.50) | RAB9ARECQLNPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8918190 | 0.69 | P2RX7 (0.52) | NPC1SMN1; SMN2HPGDGAALMNA | |
| SCHEMBL8919987 | 0.69 | SMN1; SMN2 (0.55) | RAB9ASMN1; SMN2L3MBTL1TP53GAA | |
| SCHEMBL405248 | 0.68 | ALDH1A1 (0.70) | RAB9ARECQLNPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8920203 | 0.68 | MTNR1A (0.33) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691366-A | UNSATURATED NITRO OXIME FORMED BY REACTION OF DINITROGEN TRIOXIDE WITH DIOLEFIN ETHER, SULFIDE OR AMINE TO BE USED AS VASODILATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0612315-A1 | NITRO COMPOUNDS HAVING VASODILATOR ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-08-31 | — | — | EP | disclosed |