Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.41 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921318 | 0.98 | ALDH1A1 (0.45) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL8919722 | 0.96 | ALDH1A1 (0.44) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL8417915 | 0.87 | ACACB (0.37) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL8422069 | 0.85 | CTSK (0.42) | RAB9AALDH1A1MEN1KMT2ALTA4H | |
| SCHEMBL8918241 | 0.84 | SPHK1 (0.45) | ALDH1A1S1PR5TP53S1PR1 | |
| SCHEMBL8705669 | 0.84 | ACACB (0.39) | ALDH1A1KMT2AACACB | |
| SCHEMBL8574500 | 0.84 | ACACB (0.39) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL8417738 | 0.80 | ACACB (0.34) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL8421972 | 0.80 | ACACB (0.38) | ACACB | |
| SCHEMBL8921220 | 0.78 | MCHR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691349-A | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 1997-11-25 | — | — | US | claimed |
| US-5691349-A | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 1997-11-25 | — | — | US | disclosed |