Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HRH2 | P25021 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921318 | 0.86 | ALDH1A1 (0.45) | ACACBHRH2HRH1HRH3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8919722 | 0.85 | ALDH1A1 (0.44) | ACACBHRH3ALDH1A1LMNAKMT2A | |
| SCHEMBL8919308 | 0.84 | RAB9A (0.43) | ACACBALDH1A1KMT2A | |
| SCHEMBL8417915 | 0.83 | ACACB (0.37) | ACACBHRH2HRH1HRH3ALDH1A1 | |
| SCHEMBL8418559 | 0.83 | ATM (0.44) | MAPTALDH1A1 | |
| SCHEMBL8712010 | 0.82 | CYP1A1 (0.38) | MAPTHRH3LMNAKMT2A | |
| SCHEMBL8422069 | 0.81 | CTSK (0.42) | HRH1ALDH1A1PKMKMT2A | |
| SCHEMBL8707234 | 0.81 | HRH3 (0.37) | ACACBHRH3 | |
| SCHEMBL8919982 | 0.79 | MMP13 (0.46) | ALDH1A1 | |
| SCHEMBL8421972 | 0.79 | ACACB (0.38) | ACACBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770608-A | ANTICHOLESTEROL AGENTS FOR TREATING CARDIOVASCULAR DISORDERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1998-06-23 | — | — | US | disclosed |