SCHEMBL8919959

SCHEMBL8919959

CCOc1cccc2c1C1(NC2=N)OC(C)O1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.34
KDM4E B2RXH2 3/20 0.34
PPARG P37231 1/20 0.34
STAT3 P40763 1/20 0.34
NCOA2 Q15596 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
PDK2 Q15119 1/20 0.33
DDB1 Q16531 1/20 0.33
CRBN Q96SW2 1/20 0.33
PTPRC P08575 1/20 0.33
ADORA3 P0DMS8 2/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MAPT P10636 4/20 0.32
MEN1 O00255 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8920492 0.90 CYP2A6 (0.34) ALDH1A1KDM4EHTR2AHTR2CHTR2B
SCHEMBL8922193 0.88 CYP1A2 (0.38) KDM4EMAPT
SCHEMBL8918266 0.86 PDE5A (0.36) HTR2BMAPTMEN1KMT2A
SCHEMBL8919048 0.86 PDE5A (0.36) HTR2BMAPTMEN1KMT2A
SCHEMBL8920603 0.85 ACHE (0.35) ALDH1A1KDM4EHTR2CCA1CA2
SCHEMBL8919955 0.82 ALDH1A1 (0.36) ALDH1A1KDM4EPPARGSTAT3NCOA2
SCHEMBL8920291 0.82
SCHEMBL8917808 0.80 SLC6A2 (0.35) ALDH1A1MAPTKMT2AHPGDSMN1; SMN2
SCHEMBL8919172 0.80 PDK2 (0.38) ALDH1A1KDM4EPDK2DDB1CRBN
SCHEMBL8922917 0.77 DAO (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed