Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | ACACB | O00763 | 10/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | USP14 | P54578 | 2/20 | 0.36 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418559 | 0.84 | ATM (0.44) | ALDH1A1HPGDTSHRSMN1; SMN2FDFT1 | |
| SCHEMBL8919982 | 0.81 | MMP13 (0.46) | ALDH1A1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8705669 | 0.76 | ACACB (0.39) | ALDH1A1ACACBKMT2A | |
| SCHEMBL8921229 | 0.73 | ATM (0.43) | ALDH1A1ACACBNPC1HPGDTSHR | |
| SCHEMBL8421972 | 0.72 | ACACB (0.38) | ACACB | |
| SCHEMBL8772580 | 0.71 | FDFT1 (0.71) | FDFT1 | |
| SCHEMBL21274649 | 0.70 | HTT (0.49) | ALDH1A1FFAR1TSHRRAB9AUSP14 | |
| SCHEMBL21199753 | 0.68 | ALDH1A1 (0.50) | ALDH1A1NPC1HPGDTSHRRAB9A | |
| SCHEMBL12883164 | 0.68 | ACHE (0.59) | ALDH1A1FFAR1TSHRKDM4EMEN1 | |
| SCHEMBL12883163 | 0.68 | ACHE (0.59) | ALDH1A1FFAR1TSHRKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691349-A | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 1997-11-25 | — | — | US | disclosed |