Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921096 | 0.78 | ALDH1A1 (0.35) | ALDH1A1SLC18A3L3MBTL1 | |
| SCHEMBL8707234 | 0.75 | HRH3 (0.37) | KDM4E | |
| SCHEMBL8574139 | 0.68 | CHRNA7 (0.50) | CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL10191870 | 0.67 | KMT2A (0.81) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7306300 | 0.66 | MAPT (0.71) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL2231385 | 0.66 | RAB9A (0.85) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8575554 | 0.66 | SLC18A3 (0.33) | SLC18A3 | |
| SCHEMBL8599640 | 0.65 | KMT2A (0.75) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL5856552 | 0.64 | KMT2A (0.62) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL861674 | 0.64 | SMN1; SMN2 (0.84) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691349-A | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 1997-11-25 | — | — | US | disclosed |