Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7438365 | 0.99 | AGTR1 (0.39) | AGTR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL7447901 | 0.84 | AGTR1 (0.41) | AGTR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL7440876 | 0.76 | AGTR1 (0.51) | AGTR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL7437229 | 0.74 | PRKAB2 (0.44) | AGTR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL7446686 | 0.73 | KCNN3 (0.40) | AGTR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL7440984 | 0.73 | AGTR1 (0.51) | AGTR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL7440794 | 0.72 | MEN1 (0.39) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL7434311 | 0.72 | AGTR1 (0.45) | AGTR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL7437937 | 0.71 | PTPN1 (0.44) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL7438686 | 0.71 | PRKAB2 (0.43) | AGTR1PRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602137-A | Pyrimidine compounds and their use as pharmaceuticals | BEIERSDORF-LILLY GMBH (DE) | 1997-02-11 | — | — | US | disclosed |