Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.51 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922901 | 0.95 | MAPT (0.57) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8921187 | 0.94 | MEN1 (0.56) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8920196 | 0.90 | MAPT (0.74) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL8921602 | 0.83 | MEN1 (0.61) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7464454 | 0.82 | L3MBTL1 (0.73) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8920264 | 0.82 | MEN1 (0.66) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7466702 | 0.79 | PRMT5 (0.57) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8921142 | 0.78 | MEN1 (0.58) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7459655 | 0.78 | ALDH1A1 (0.58) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7459301 | 0.78 | L3MBTL1 (0.56) | MAPTMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |