Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922901 | 0.97 | MAPT (0.57) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL8920117 | 0.94 | MAPT (0.60) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL8920196 | 0.86 | MAPT (0.74) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL8921602 | 0.84 | MEN1 (0.61) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL8924828 | 0.80 | SMN1; SMN2 (0.43) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL7464454 | 0.79 | L3MBTL1 (0.73) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL8920264 | 0.79 | MEN1 (0.66) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL8920119 | 0.78 | SMN1; SMN2 (0.51) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL8920108 | 0.77 | RAB9A (0.46) | MEN1KMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL7466702 | 0.75 | PRMT5 (0.57) | MEN1KMT2AMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |
| EP-0685466-A1 | 3-Heteroaliphatyle-and 3-hetero-(aryle)-aliphatyle-2(1H)-quinolone derivatives | CIBA-GEIGY AG (CH) | 1995-12-06 | — | — | EP | disclosed |