Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920782 | 0.85 | KDM4E (0.73) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL8920754 | 0.84 | ALDH1A1 (0.48) | KDM4EALDH1A1EGFRMEN1KMT2A | |
| SCHEMBL8923424 | 0.78 | KDM4E (0.69) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL8921296 | 0.77 | KDM4E (0.67) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL8923373 | 0.76 | KDM4E (0.74) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL8922218 | 0.75 | KDM4E (1.00) | KDM4EALDH1A1MAPTHPGDPOLB | |
| SCHEMBL8923299 | 0.71 | KDM4E (0.72) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL20510183 | 0.71 | LMNA (0.71) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL8921828 | 0.70 | ALDH1A1 (0.61) | KDM4EALDH1A1MAPTHPGDPOLB | |
| SCHEMBL3542412 | 0.69 | LMNA (0.72) | KDM4EALDH1A1MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |