Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919243 | 0.87 | L3MBTL1 (0.38) | L3MBTL1ACHEGRIN2BOPRM1 | |
| Oxalic Acid SCHEMBL8919232 | 0.83 | MEN1 (0.41) | MEN1KMT2AL3MBTL1GRIN2BPKM | |
| Oxalic Acid SCHEMBL7464359 | 0.75 | CHIA (0.46) | MEN1KMT2AL3MBTL1GRIN2BALDH1A1 | |
| SCHEMBL8920236 | 0.75 | DRD4 (0.41) | MEN1KMT2AL3MBTL1GRIN2BOPRM1 | |
| SCHEMBL8922923 | 0.74 | CRBN (0.48) | GRIN2BALDH1A1 | |
| Hydrochloric Acid SCHEMBL8919035 | 0.74 | GRIN2B (0.39) | MEN1KMT2AL3MBTL1GRIN2BPKM | |
| Hydrochloric Acid SCHEMBL8919208 | 0.74 | DRD4 (0.41) | MEN1KMT2AL3MBTL1GRIN2BOPRM1 | |
| SCHEMBL8919777 | 0.74 | CHIA (0.42) | MEN1KMT2AL3MBTL1GRIN2BPKM | |
| Oxalic Acid SCHEMBL7470413 | 0.74 | KMT2A (0.57) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| Oxalic Acid SCHEMBL7462899 | 0.73 | ALDH1A1 (0.57) | MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591751-A | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-07 | — | — | US | disclosed |