SCHEMBL8920567

SCHEMBL8920567

COC1(OC)NC(=N)c2cccc(Sc3ccc(C(C)(C)C)cc3)c21

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.38
HTR1A P08908 1/20 0.38
HTR3A P46098 1/20 0.38
P4HB P07237 1/20 0.34
SLC6A9 P48067 1/20 0.33
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8920434 0.87 DHFR (0.36) DHFRHTR1AHTR3AP4HBSLC6A9
SCHEMBL8919194 0.82 DHFR (0.38) DHFRHTR1AHTR3AP4HBSLC6A9
SCHEMBL8919866 0.77 MAOA (0.33)
SCHEMBL8919057 0.77 MAOA (0.33) P4HB
SCHEMBL7815267 0.74 CA2 (0.33)
SCHEMBL8919084 0.71 DHFR (0.35) DHFRHTR1AHTR3ASLC6A9
SCHEMBL7831614 0.69 DAO (0.33) ALDH1A1
SCHEMBL7824598 0.68 ALDH1A1 (0.34) ALDH1A1
SCHEMBL7824782 0.68 ALDH1A1 (0.34) ALDH1A1
SCHEMBL7816249 0.68 NSD2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed