Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27479655 | 0.80 | KDM4E (0.38) | ABCB1DRD2ALDH1A1HTR6KDM4E | |
| SCHEMBL8916736 | 0.77 | ABCB1 (0.53) | ABCB1HTR1ASIGMAR1SETD7DRD2 | |
| SCHEMBL19604914 | 0.76 | ALDH1A1 (0.46) | ABCB1HTR1ASIGMAR1SETD7ALDH1A1 | |
| SCHEMBL19606300 | 0.75 | SETD7 (0.44) | ABCB1HTR1ASIGMAR1SETD7ALDH1A1 | |
| SCHEMBL26157120 | 0.72 | HTR6 (0.44) | ABCB1SIGMAR1SETD7DRD2DRD3 | |
| SCHEMBL256663 | 0.71 | SIGMAR1 (0.63) | HTR1ASIGMAR1 | |
| SCHEMBL18936739 | 0.71 | SIGMAR1 (0.66) | HTR1ASIGMAR1HTR6 | |
| SCHEMBL10254250 | 0.69 | SIGMAR1 (0.52) | SIGMAR1HTR6 | |
| SCHEMBL27902404 | 0.69 | SIGMAR1 (0.53) | HTR1ASIGMAR1DRD2DRD3KDM4E | |
| SCHEMBL10635938 | 0.68 | HTR6 (0.39) | ABCB1SIGMAR1SETD7DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625046-A | Hydroxyl projecting groups for organic synthesis | KING'S COLLEGE LONDON (GB) | 1997-04-29 | — | — | US | disclosed |
| US-5436331-A | Etherification with N-aryl-4-alkoxy-1,2,5,6-tetrahydropyidine | KINGS COLLEGE LONDON (GB) | 1995-07-25 | — | — | US | disclosed |
| EP-0298982-B1 | PROTECTING GROUPS FOR ORGANIC SYNTHESIS | KING'S COLLEGE LONDON (GB) | 1991-08-28 | — | — | EP | disclosed |