SCHEMBL8920673

SCHEMBL8920673

CC1OC2(NC(=N)c3c(Sc4ccc(C(C)(C)C)cc4)cccc32)O1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.35
HTR1A P08908 1/20 0.35
HTR3A P46098 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8919194 0.79 DHFR (0.38) DHFRHTR1AHTR3A
SCHEMBL9092640 0.77 PTGIR (0.30)
SCHEMBL8919084 0.75 DHFR (0.35) DHFRHTR1AHTR3A
SCHEMBL8919192 0.71 NPC1 (0.31)
SCHEMBL8920209 0.69 NPC1 (0.31)
SCHEMBL8921486 0.69 PDK2 (0.34) HTR1A
SCHEMBL8920567 0.64 DHFR (0.38) DHFRHTR1AHTR3A
SCHEMBL10973924 0.62 MAPT (0.58) DHFRHTR1AHTR3A
SCHEMBL8920434 0.62 DHFR (0.36) DHFRHTR1AHTR3A
SCHEMBL8919202 0.62 CA2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed