Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acridine SCHEMBL8917092 | 0.83 | TLR8 (0.42) | TLR8ALDH1A1HPGDGLAMAPT | |
| Acridine SCHEMBL27681561 | 0.81 | ALDH1A1 (0.65) | TLR8ALDH1A1HPGDGLAMAPT | |
| Acridine SCHEMBL28232031 | 0.81 | ALDH1A1 (0.65) | TLR8ALDH1A1HPGDGLAMAPT | |
| Acridine SCHEMBL8670269 | 0.80 | TLR8 (0.38) | TLR8ALDH1A1HPGDGLAMAPT | |
| Acridine SCHEMBL28205217 | 0.79 | ALDH1A1 (0.62) | TLR8ALDH1A1HPGDGLAMAPT | |
| Acridine SCHEMBL29014290 | 0.76 | ALDH1A1 (0.68) | TLR8ALDH1A1HPGDGLAMAPT | |
| SCHEMBL9248684 | 0.76 | LMNA (0.41) | TSHRLMNA | |
| SCHEMBL599470 | 0.74 | TLR8 (0.44) | TLR8ALDH1A1HPGDGLAMAPT | |
| Acridine SCHEMBL25416084 | 0.73 | ALDH1A1 (0.54) | TLR8ALDH1A1HPGDGLAMAPT | |
| Acridine SCHEMBL8577853 | 0.73 | ALDH1A1 (0.58) | TLR8ALDH1A1HPGDGLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665328-A | USING SELECTED DYE AS BINDING AGENT WITHOUT PRODUCING DETRIMENTAL EFFECT ON MORPHOLOGY OR PHYSIOLOGICAL FUNCTION OF CELLS | PHANOS TECHNOLOGIES, INC. (US) | 1997-09-09 | — | — | US | disclosed |