SCHEMBL8920863

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14496720	0.90	HPGD (0.39)	NPC1RAB9ACASP3SENP7POLB
	SCHEMBL8919564	0.90	HDAC1 (0.41)	NPC1RAB9AHPGDMAPTSMN1; SMN2
	SCHEMBL8919704	0.89	ATM (0.41)	NPC1RAB9APOLBMEN1KMT2A
	SCHEMBL3134678	0.85	HDAC1 (0.46)	NPC1RAB9AHPGDMAPTSMN1; SMN2
	SCHEMBL8922892	0.82	LMNA (0.41)	NPC1RAB9AMEN1KMT2AHPGD
	SCHEMBL3143373	0.81	LMNA (0.37)	NPC1RAB9AMEN1KMT2AMAPT
	SCHEMBL14496721	0.80	POLB (0.41)	NPC1RAB9APOLBMEN1KMT2A
	SCHEMBL3036162	0.80	MEN1 (0.46)	NPC1RAB9ACASP3SENP7POLB
	SCHEMBL8919642	0.79	HDAC1 (0.43)	NPC1RAB9APOLBHPGDMAPT
	Bromide SCHEMBL3142384	0.78	HDAC1 (0.38)	SMN1; SMN2ALDH1A1USP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.