SCHEMBL8919642

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8919564	0.89	HDAC1 (0.41)	HDAC1RAB9AL3MBTL1NPC1TNF
	SCHEMBL8919704	0.89	ATM (0.41)	HDAC1RAB9ANPC1MAPTGAA
	SCHEMBL14496721	0.88	POLB (0.41)	RAB9ANPC1MAPTUSP2LMNA
	SCHEMBL3138729	0.85	MCHR1 (0.39)	HDAC1GAAHTR2AHTR2CHTR2B
	SCHEMBL3134678	0.85	HDAC1 (0.46)	HDAC1RAB9AL3MBTL1NPC1TNF
	SCHEMBL3035931	0.83	RAB9A (0.47)	RAB9AL3MBTL1NPC1TNFNOD1
	SCHEMBL8914383	0.83	ALDH1A1 (0.39)	RAB9AMAPTUSP2LMNAPOLB
	SCHEMBL8922892	0.82	LMNA (0.41)	RAB9ANPC1MAPTGAAMAPK1
	SCHEMBL3142846	0.80	SMN1; SMN2 (0.38)	MAPTTDP1HTR2AHTR2CHTR2B
	SCHEMBL8920863	0.79	NPC1 (0.43)	RAB9ANPC1MAPTGAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.