Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NMT1 | P30419 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19216503 | 0.84 | TDP1 (0.55) | TDP1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL19427448 | 0.82 | ALDH1A1 (0.52) | RAB9AALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL30320165 | 0.81 | RAB9A (0.55) | TDP1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5705038 | 0.81 | TDP1 (0.52) | TDP1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL11373630 | 0.81 | TDP1 (0.52) | TDP1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL19427499 | 0.79 | NPC1 (0.63) | RAB9ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL4770587 | 0.79 | TSHR (0.68) | TDP1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL14557542 | 0.78 | GAA (0.61) | TDP1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL28431265 | 0.78 | TDP1 (0.57) | TDP1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL9116925 | 0.76 | RAB9A (0.46) | TDP1RAB9ASMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194660-A | Processes for producing carbamates and isocyanates | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0083096-B1 | PRODUCTION OF URETHANE COMPOUNDS | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1987-02-25 | — | — | EP | disclosed |
| US-4621149-A | PLATINUM GROUP METAL HALOGEN OR HALOGEN COMPOUND | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1986-11-04 | — | — | US | disclosed |
| EP-0083096-A2 | Production of urethane compounds | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-07-06 | — | — | EP | disclosed |