Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.42 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919777 | 0.86 | CHIA (0.42) | L3MBTL1L3MBTL3CHIAABL1RIN1 | |
| Hydrochloric Acid SCHEMBL8919035 | 0.86 | GRIN2B (0.39) | BRD4L3MBTL1CHIAABL1RIN1 | |
| Oxalic Acid SCHEMBL8919232 | 0.85 | MEN1 (0.41) | BRD4L3MBTL1CHIAABL1RIN1 | |
| Hydrochloric Acid SCHEMBL8921524 | 0.84 | ALDH1A1 (0.41) | GRIN2BKMT2AMEN1NPSR1 | |
| SCHEMBL8919205 | 0.84 | HTT (0.45) | L3MBTL1CHIAGRIN2BKMT2AMEN1 | |
| SCHEMBL8922923 | 0.82 | CRBN (0.48) | CHIAGRIN2BDRD4 | |
| SCHEMBL9207045 | 0.79 | CCR3 (0.41) | L3MBTL1CHIAGRIN2BHTR2BKMT2A | |
| Hydrochloric Acid SCHEMBL8918415 | 0.78 | CCR3 (0.41) | L3MBTL1CHIAGRIN2BHTR2BKMT2A | |
| SCHEMBL8919197 | 0.77 | CRBN (0.47) | GRIN2BDRD4MCHR1 | |
| Hydrochloric Acid SCHEMBL7470903 | 0.75 | HSD11B1 (0.47) | CHIAGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591751-A | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0636128-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-01 | — | — | EP | disclosed |
| WO-1994019339-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-01 | — | — | WO | disclosed |