Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 2/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920449 | 0.88 | CTSK (0.47) | MAPTMEN1KMT2AAPPCTSK | |
| SCHEMBL8921567 | 0.86 | SMN1; SMN2 (0.47) | MAPTMEN1KMT2AAPPCTSK | |
| SCHEMBL8920496 | 0.85 | MAPT (0.41) | MAPTMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL8919472 | 0.85 | MAPT (0.41) | MAPTMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL8921657 | 0.85 | MAPT (0.41) | MAPTMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL8920403 | 0.83 | AKT1 (0.46) | KLK5CTSKAKT1 | |
| SCHEMBL8921589 | 0.83 | AKT1 (0.46) | KLK5CTSKAKT1 | |
| SCHEMBL8923100 | 0.83 | AKT1 (0.46) | KLK5CTSKAKT1 | |
| SCHEMBL25353524 | 0.81 | AKT1 (0.53) | APPAKT1NPSR1TDP1 | |
| SCHEMBL18087667 | 0.81 | AKT1 (0.53) | APPAKT1NPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637613-A | ANTITUMOR AGENT; IMMUNOSUPPRESSANTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1997-06-10 | — | — | US | disclosed |